GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BRCA | cis | rs1971762 | 1 | rs10876481 | chr12:54066743 | ATP5G2 | chr12:54058945-54070512:- | 0.09 | 3.37 | 0.000769 | Height |
| BRCA | cis | rs703842 | 1 | rs10877012 | chr12:58162085 | B4GALNT1 | chr12:58019551-58026985:- | 0.13 | 3.85 | 0.000124 | Multiple sclerosis |
| BRCA | cis | rs703842 | 1 | rs10877012 | chr12:58162085 | FAM119B | chr12:58166383-58176323:+ | 0.41 | 10.06 | 8.45E-23 | Multiple sclerosis |
| BRCA | cis | rs703842 | 1 | rs10877012 | chr12:58162085 | TSFM | chr12:58176536-58191367:+ | -0.33 | -9.69 | 2.36E-21 | Multiple sclerosis |
| BRCA | cis | rs703842 | 1 | rs10877012 | chr12:58162085 | XRCC6BP1 | chr12:58335445-58351051:+ | -0.17 | -4.65 | 3.65E-6 | Multiple sclerosis |
| BRCA | cis | rs703842 | 1 | rs10877013 | chr12:58165085 | B4GALNT1 | chr12:58019551-58026985:- | 0.13 | 3.79 | 0.000158 | Multiple sclerosis |
| BRCA | cis | rs703842 | 1 | rs10877013 | chr12:58165085 | FAM119B | chr12:58166383-58176323:+ | 0.42 | 10.69 | 2.04E-25 | Multiple sclerosis |
| BRCA | cis | rs703842 | 1 | rs10877013 | chr12:58165085 | TSFM | chr12:58176536-58191367:+ | -0.32 | -9.76 | 1.32E-21 | Multiple sclerosis |
| BRCA | cis | rs703842 | 1 | rs10877013 | chr12:58165085 | XRCC6BP1 | chr12:58335445-58351051:+ | -0.17 | -4.77 | 2.06E-6 | Multiple sclerosis |
| BRCA | cis | rs703842 | 1 | rs10877014 | chr12:58167661 | B4GALNT1 | chr12:58019551-58026985:- | 0.13 | 3.85 | 0.000124 | Multiple sclerosis |
| BRCA | cis | rs703842 | 1 | rs10877014 | chr12:58167661 | FAM119B | chr12:58166383-58176323:+ | 0.42 | 10.8 | 7.25E-26 | Multiple sclerosis |
| BRCA | cis | rs703842 | 1 | rs10877014 | chr12:58167661 | TSFM | chr12:58176536-58191367:+ | -0.32 | -9.79 | 1.01E-21 | Multiple sclerosis |
| BRCA | cis | rs703842 | 1 | rs10877014 | chr12:58167661 | XRCC6BP1 | chr12:58335445-58351051:+ | -0.17 | -4.77 | 2.14E-6 | Multiple sclerosis |
| BRCA | cis | rs703842 | 1 | rs10877015 | chr12:58167788 | B4GALNT1 | chr12:58019551-58026985:- | 0.14 | 3.94 | 8.75E-5 | Multiple sclerosis |
| BRCA | cis | rs703842 | 1 | rs10877015 | chr12:58167788 | FAM119B | chr12:58166383-58176323:+ | 0.41 | 10.16 | 3.39E-23 | Multiple sclerosis |